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Fat Cells

Fat cells contain two types of receptors for catecholamines that are diametrically opposed in function.
These are known as alpha- and beta-receptors and while the physiology is quite complex, it boils down to this: alpha-receptors hinder lipolysis and beta-receptors trigger it.
Thus, fat cells with a high amount of beta-receptors are relatively easy to mobilize whereas those with a high amount of alpha-receptors aren’t.
This is why, when you start a fat loss regimen, you see immediate results in certain areas of your body like your chest, arms, and face, but next-to-nothing in other areas like your stomach, hips, and thighs.
One of the primary reasons why certain fat stores, like belly fat, are so “stubborn” is the fat cells themselves are very resistant to mobilization (they contain many more alpha-receptors than beta).

No matter your genetics or hormones, you can have the lean, ripped stomach you desire. And it can be easier than you ever thought possible…if you know exactly what you’re doing and why. And that knowledge begins with a physiological understanding of how “fat burning” actually works.

https://www.ncbi.nlm.nih.gov/pubmed/38720
https://www.ncbi.nlm.nih.gov/pubmed/8401205
http://www.ncbi.nlm.nih.gov/pubmed/8387538

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